Brazilian Journal of Pulmonology

ISSN (on-line): 1806-3756 | ISSN (printed): 1806-3713


Publication continuous and bimonthly

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Pulmonologists, awake!

Acorda pneumologista !

Geraldo Lorenzi Filho, Flávio Magalhães, Carlos Alberto de Assis Viegas

J Bras Pneumol.2006;32(4):382-384

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Obesity hypoventilation syndrome: a current review

Síndrome de obesidade-hipoventilação: uma revisão atual

Rodolfo Augusto Bacelar de Athayde1,2,a, José Ricardo Bandeira de Oliveira Filho1,b, Geraldo Lorenzi Filho2,c, Pedro Rodrigues Genta2,d

J Bras Pneumol.2018;44(6):510-518

Abstract Portuguese Text

Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of venous bicarbonate in screening for OHS, and diagnostic criteria for OHS that eliminate the need for polysomnography. In addition, we review advances in the treatment of OHS, including behavioral measures, and recent studies comparing the efficacy of continuous positive airway pressure with that of noninvasive ventilation.


Keywords: Obesity; Obesity hypoventilation syndrome; Noninvasive ventilation.


Another milestone for the Brazilian Journal of Pulmonology

Um novo marco no Jornal Brasileiro de Pneumologia

Geraldo Lorenzi Filho

J Bras Pneumol.2004;30(4):401-401

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