Brazilian Journal of Pulmonology

ISSN (on-line): 1806-3756 | ISSN (printed): 1806-3713


Publication continuous and bimonthly

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Year 1999 - Volume 25  - Number 6  (November/December)


1 - O redescobrimento luso-brasileiro

Maria João Marques Gomes, Francisco Elmano Marques de Souza, Renato Soto-Mayor, Luiz Carlos Corrêa da Silva, Antônio Ramalho de Almeida, Bruno Carlos Palombini

J Bras Pneumol.1999;25(6):5-


Original Article

2 - Open, controlled clinical assay of the addition of ipratropium bromide to fenoterol in the treatment of acute asthma crisis in adults

Ensaio clínico, aberto, controlado sobre a adição de brometo de ipratrópio ao fenoterol no tratamento da crise de asma em adultos

Solange Diccini, Clystenes Odyr Soares Silva, Jorge Nakatani, Carlos Alberto de Castro Pereira

J Bras Pneumol.1999;25(6):301-308

Abstract PDF PT Portuguese Text

Repeated dosis of inhaled β2-agonists have been used in the treatment of acute asthma. The effect of added ipratropium bromide (IB) to β2-agonist is controversial in adults. Objective: To evaluate if addition of IB to fenoterol, in repeated doses, induces a greater bronchodilation, a greater reversion of the attack, and discharge from emergency unit in adults with acute severe asthma. Setting: Pneumology Emergency Department, Unifesp-Hospital São Paulo, in the period from July 1995 to February 1997. Type of study: Open, randomized and parallel study. Discharge from the hospital: FEV1 and PEF ≥ 60% of the predicted value. Methods: 120 patients with FEV1 and PEF ≤ 50% of the predicted value were divided into two groups (N = 60): fenoterol (F) and ipratropium bromide + fenoterol (IBF). Each group received inhalation treatment through a metered-dose inhaler (MDI) attached to a holding chamber, administered at 30-minute interval, for a total of three treatments. In the group F four puffs of fenoterol (400 μg) were administered, and in the IBF group, 160 μg of BI and 400 μg of fenoterol (four puffs). Results: The patients did not differ from basal PEF (F = 36 ± 7% vs IBF = 35 ± 9% predicted) and basal FEV1 (F = 33 ± 9% vs IBF = 32 ± 9% predicted). Thirty-two patients of group F and 33 of group IBF were discharged from hospital after the inhalation treatment. The final FEV1 and PEF after inhalation treatments were F = 60 ± 13% vs IBF = 61 ± 11% e F = 74 ± 18% vs IBF = 77 ± 13% (NS). Conclusion: The addition of ipratropium bromide to fenoterol results in insignificant functional effect and without clinical impact in the treatment of acute asthma in adults.


Keywords: Fenoterol. Ipratropium. Status asthmaticus. Respiratory therapy.



3 - Suitability of Health Science key words for indexing master's degree theses and dissertations in the area of respiratory diseases

Adequação dos descritores em Ciências da Saúde para a indexação de dissertações acadêmicas, na área de doenças respiratórias

J Bras Pneumol.1999;25(6):

Abstract PDF PT Portuguese Text

Introduction: The process of indexing consisted of two phases: firstly, to identify and represent the intellectual contents of a document; and secondly, the translation of the subject analysis into a specified language, with the aid of key words. At the Instituto de Doenças do Tórax da UFRJ medical library, the indexing was performed through a controlled vocabulary - the MeSH (Medical Subject Headings). The purpose of this study was to identify if the authors' subject headings were adequate for indexing Master's degree theses and dissertations on respiratory diseases. Method: The key words of 29 Master theses and dissertations, from 1990 through 1996, were studied. Results: The data collection showed that 29 authors employed 101 key words (3.48 headings/author). Among the 101 key words, 47 (47%) were adequate. Conclusion: Forty-seven per cent of the key words employed, on Master's degree theses and dissertations on respiratory diseases (IDT-UFRJ, 1990-1996), were adequate.


Keywords: Abstracting and indexing. Key words. Dissertations, academic.


Original Article

4 - Smoking and alcohol drinking practices among employees of Universidade Estadual do Ceará

Tabagismo e etilismo em funcionários da Universidade Estadual do Ceará

Maria Olganê Dantas Sabry, Helena Alves de Carvalho Sampaio, Marcelo Gurgel Carlos da Silva

J Bras Pneumol.1999;25(6):313-320

Abstract PDF PT Portuguese Text

The aim of the present study was to identify smoking and alcohol drinking practices among Universidade Estadual do Ceará employees in the city of Fortaleza. The study used 317 employees as subjects. An interview questionnaire containing personal, socioeconomic, tobacco and alcohol consumption data was applied. The tabulation and analysis were made by Epi-Info 6.0. 157 of the interviewed subjects were male and 160 were female, the most prevalent age bracket being 30-49 years of age, and high level of instruction. 146 workers showed a family income starting from 10 minimal living wages per month. 83 workers were considered smokers, and a higher prevalence was detected among males (56). Mean tobacco consumption was 12.3 cigarettes a day, a practice that took place in the last 23.2 years. Alcohol was ingested by 183 employees and the prevalence was also higher among males. The consumption occurred mainly on weekends or rarely. The most ingested drink was beer - 96, followed by Brazilian white rum - 20 employees. The mean daily consumption of ethanol was 29.9 g. The ones who were both smokers and drinkers were mainly males. The instruction and income level were higher among smoking females and the income level was higher among drinking females. Although the prevalence of tobacco and alcohol consumption was low, it is a risk of chronicdegenerative diseases, specially in relation to the ethanol ingested by males. It is necessary to continue this study to provide a deeper association among the different environmental variables.


Keywords: Smoking. Alcoholism. Employees. Universities.



5 - Curso de epidemiologia básica para pneumologistas - 4ª parte - Epidemiologia clínica

Ana M.B. Menezes, Iná da S. dos Santos

J Bras Pneumol.1999;25(6):321-326


Review Article

7 - Compliance curves or pressure-volume curves in acute respiratory failure

Curvas de complacência ou curvas pressão-volume na insuficiência respiratória aguda

Silvia Regina Rios Vieira

J Bras Pneumol.1999;25(6):335-339

Abstract PDF PT Portuguese Text

The goal of this paper is to review the use of pressure-volume (P-V) curves or compliance curves in patients with acute respiratory failure (ARF) - acute lung injury (ALI), and acute respiratory distress syndrome (ARDS). The most important papers published in English language literature concerning P-V curves in ARF were found in Medline and reviewed. Ideally, recommendation is made to calculate P-V curves in all patients with ARF in order to achieve adequate monitoring and management considering data obtained from the curves, such as lower inflexion point, upper inflexion point, and static compliance. The methods used to obtain P-V curves are supersyringe, multiple inspiratory occlusions and continuous flow. All of them are similar if low continuous flow is used and if care is taken to allow lung emptying and to avoid intrinsic PEEP (positive end expiratory pressure) before accomplishing the curves. In this way continuous flow can be a simple, inexpensive, secure and reliable method to be carried out at bedside in order to obtain P-V curves that allow for a better monitoring and management of patients with ARF.


Keywords: Acute lung injury. Acute respiratory distress syndrome. Pressure-volume curves.


Case Report

8 - Pulmonary embolism resulting from metastatic choriocarcinoma with atypical presentation: report of a case

Embolia pulmonar decorrente de coriocarcinoma metastático com apresentação atípica

Teresa de Jesus Jhayya, Andreia Luisa Simões Francisco, Clystenes Odyr Soares Silva, Rimarcs G. Ferreira

J Bras Pneumol.1999;25(6):340-342

Abstract PDF PT Portuguese Text

A case is presented of a 36 year-old woman, with metastatic lung choriocarcinoma with atypical clinical and radiological presentation. The finding of pulmonary hypertension indicated the possibility of pulmonary thromboembolism, still, the definitive diagnosis and cause of pulmonary embolism were done in the autopsy. The authors discuss the manners of choriocarcinoma metastasis presentation, its repercussions and the latent period which may exist until it presents evidence of neoplasm.


Keywords: Choriocarcinoma. Pulmonary embolism.


9 - Adenoid cystic carcinoma of the trachea: treatment by removing the larynx, trachea, and esophagus, and mediastinal tracheostomy

Carcinoma adenóide cístico de traquéia: tratamento pela laringotráqueo-esofagectomia e traqueostomia mediastinal

Manoel Ximenes Netto, Gutemberg F. Rego, André L.a. Carvalho, Hélcio L. Miziara

J Bras Pneumol.1999;25(6):343-346

Abstract PDF PT Portuguese Text

The authors describe the case of a 54 year-old female with adenoid cystic carcinoma of the trachea at the cricoid level upon whom extensive surgical resection was performed, including the larynx, part of the trachea and esophagus. Reconstruction of the digestive tract was done by means of a gastric tube and the airway with a mediastinal tracheostomy. Five years after the original procedure there was a local cutaneous recurrence which was removed. Seven years later the disease recurred in the mediastinum, which responded to irradiation. The patient is alive and well eight years and five months after the operation.


Keywords: Trachea. Neoplasm. Carcinoma, adenoid cystic. Tracheostomy.


10 - Pseudohemoptysis caused by leishmaniasis

Pseudo-hemoptise por leishmaniose

Saulo Maia D'Avila Melo, João Carlos Todt Neto, Leila Caroline Faria de Andrade

J Bras Pneumol.1999;25(6):347-350

Abstract PDF PT Portuguese Text

A case of larynx mucosa leishmaniasis was initially misdiagnosed with lung tuberculosis, because the first symptom was pseudohemoptysis. The histologic appearance confirmed the diagnosis. The primary location in the larynx is exceptional. It is very important for bronchoscopists to have a broad experience in upper airways to make an exact diagnosis.


Keywords: Leishmaniasis. Hemoptysis.



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